I am Hatem Ali
We summarize the associations corresponding to the top versus bottom third of the baseline FGF-23 concentrations. In studies where different measures of association were reported, we
are trying to calculate a measure of association corresponding to the top versus bottom third of FGF-23concentration .
in some studies, associations were reported for top versus bottom quintile, quartile or half of the FGF-23 distribution. in some other studies, associations were reported per unit of standard deviation (SD)
I wonder if you can help me to convert the risk ratio as reported in the studies and calculate the risk ratio and confidence interval of top versus bottom tertiles?
(ln/unit=per unit on lnFGF-23 scale; Q4vsQ1=top quartile vs bottom quartile; log/SD or ln/SD=per SD on logFGF-23/lnFGF-23 scale)
Example of the data I got is :
We summarize the associations corresponding to the top versus bottom third of the baseline FGF-23 concentrations. In studies where different measures of association were reported, we
are trying to calculate a measure of association corresponding to the top versus bottom third of FGF-23concentration .
in some studies, associations were reported for top versus bottom quintile, quartile or half of the FGF-23 distribution. in some other studies, associations were reported per unit of standard deviation (SD)
I wonder if you can help me to convert the risk ratio as reported in the studies and calculate the risk ratio and confidence interval of top versus bottom tertiles?
(ln/unit=per unit on lnFGF-23 scale; Q4vsQ1=top quartile vs bottom quartile; log/SD or ln/SD=per SD on logFGF-23/lnFGF-23 scale)
Example of the data I got is :
| Author | Risk ratio (95% CI) as reported in study report1; comparison |
| Parker 2010 | 1.05 (0.85, 1.3); ln/unit |
| di Giuseppe 2015 | 1.62 (1.07, 2.45); Q4vsQ1 |
| Ix* 2012 | 1.19 (0.77, 1.83); Q4vsQ1 |
| Ix** 2012 | 1.29 (0.75, 2.22); Q4vsQ1 |
| Kendrick 2011 | 2.44 (1.25,4.76); Q4vsQ1 |
| Moe 2015 | 1.2 (1.02,1.41); log/SD |
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