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  • Problem with 95% Conf. interval

    Hi All,

    I am trying to calculate the proportion of two specific variables and compare the difference between these two population proportions. From the table below, In the 67 samples, the proportion of co-infection with vaccine virus is 2/7 (29%), while the proportion of non-vaccine virus with co-infection is 11/60 (18%).
    I have chosen the Two-sample test of proportion. I am not sure about the 95% CI for the proportion of the co-infection with vaccine virus. Isn't the possible range of values is 0 to 100%? What will be the right test to workout the CI for the proportion? Many thanks.

    Coinfection vaccine virus absent (0) present (1) Total
    absent (0) 49 5 54
    present (1) 11 2 13
    total 60 7 67
    code:
    . prtest coinfection, by(vaccine)

    Two-sample test of proportion 0: Number of obs = 60
    1: Number of obs = 7
    -----------------------------------------------------------------------------------------------------------------
    Variable | Mean Std. Err. z P>|z| [95% Conf. Interval]
    ---------------+------------------------------------------------------------------------------------------------
    0 | .1833333 .0499537 .0854259 .2812408
    1 | .2857143 .1707469 -.0489436 .6203721
    ---------------+------------------------------------------------------------------------------------------------
    diff | -.102381 .1779042 -.4510667 .2463048
    | under Ho: .1579452 -0.65 0.517
    -----------------------------------------------------------------------------------------------------------------
    diff = prop(0) - prop(1) z = -0.6482
    Ho: diff = 0

    Ha: diff < 0 Ha: diff != 0 Ha: diff > 0
    Pr(Z < z) = 0.2584 Pr(|Z| < |z|) = 0.5169 Pr(Z > z) = 0.7416


  • #2
    The method for calculating confidence intervals in -prtest- is based on a normal theory approximation. That approximation works poorly when there are proportions that are close to 0 or 1. You can get better confidence intervals with the -ci proportions- command.

    Comment


    • #3
      Thank you very much. I will try the cii command.

      Comment

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