I would like to do the following:
1- simulate 1000 observations
2 - simulate a continuous biomarker which can be normally distributed with a given mean and given standard deviation and simulate a binary outcome, and ensure the following:
a] the ROC AUC is 0.85
b] when fitting a logistic regression on the association between the predictor continuous biomarker on the binary outcome, I obtain an odds ratio of 1.12 (which would mean that for 1 unit increase of the biomarker, the odds of the event increase by 12%)
How do I do this in STATA or R?
Thanks
A
1- simulate 1000 observations
2 - simulate a continuous biomarker which can be normally distributed with a given mean and given standard deviation and simulate a binary outcome, and ensure the following:
a] the ROC AUC is 0.85
b] when fitting a logistic regression on the association between the predictor continuous biomarker on the binary outcome, I obtain an odds ratio of 1.12 (which would mean that for 1 unit increase of the biomarker, the odds of the event increase by 12%)
How do I do this in STATA or R?
Thanks
A
