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  • Meta forestplot Hartung-Knapp variance correction sub-groups

    Hello!

    I am currently conducting a meta-analysis of a small study number (n=3) with different subgroups (3 disease outcomes). I am using a random effects meta-analysis with a Hartung-Knapp variance correction applied to the DerSimonian-Laird model.

    I am trying to create a single forestplot depicting the results of the different sub-groups with the Hartung-Knapp variance correction applied to the overall subgroup effectsizes. However, I am unable to figure this out. When using the code below I get an error message as se(khartung) is applied to the overall effect size obtained not the subgroup overall effectsizes.

    option subgroup() may not be combined with option se().

    Code:
    meta set lnrr selnrr, studylabel(author_year_pub)
    meta forestplot, eform random(dlaird) se(khartung) subgroup(outcome)
    I have also tried to use admetan, but when using hksj there I also receive an error message:

    option hksj not allowed
    Error in admetan.BuildResultsSet
    (Note: meta-analysis model was fitted successfully)


    I hope I have explained my problem clearly! Is there anyone that might know a solution to this?

    Best wishes,

  • #2
    Dear Kim,

    I can't speak for meta forestplot, other than to agree with you -- it looks like this combination of options is currently invalid. Possibly this will be corrected in a later version.

    But admetan should work (and indeed does work with my own data). Would it be possible to supply a sample of your data and code using dataex, so that I can try to diagnose the issue?

    Best wishes,

    David.

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